Drugs & Vitamins

Ziana Active Ingredients: Clindamycin and tretinoin skin gel Representative Names: Ziana Available Product Images: What is Clindamycin; Tretinoin skin gel? What should I tell my health care provider before I take this medicine? How should this medicine be used? What if I miss a dose? What drug(s) may interact with Clindamycin; Tretinoin? What side effects may I notice from receiving Clindamycin; Tretinoin? What should I watch for while taking Clindamycin; Tretinoin? Where can I keep my medicine? What is Clindamycin; Tretinoin skin gel? (Back to top) CLINDAMYCIN; TRETINOIN (Ziana™) gel has an antibiotic and naturally occurring form of vitamin A. It is used on the skin to treat acne. What should I tell my health care provider before I take this medicine? (Back to top) They need to know if you have any of these conditions: •diarrhea •inflammatory bowel disease •stomach problems like colitis •sunburn •an unusual reaction to clindamycin, tretinoin, vitamin A, other medicines, foods, dyes, or preservatives •pregnant or trying to get pregnant •breast-feeding How should this medicine be used? (Back to top) This medicine is for use on the skin only. Follow the directions on the prescription label. Use at bedtime. Wash hands before and after use. Gently wash your face with a mild, non-medicated soap before use. Pat the skin dry. Apply a pea-size amount of the gel to your fingertip and gently spread it over your face. Do not use more than once per day. Using too much of this medicine may irritate or increase the irritation of your skin, and will not give faster or better results. Avoid applying this medicine to your eyes, ears, nostrils, angles of the nose, and mouth. It is important to use this medicine for the full course prescribed by your prescriber or health care professional, even if you think your condition is better. Do not stop using except on your prescriber's advice. Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed. What if I miss a dose? (Back to top) If you miss a dose, apply it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses. What drug(s) may interact with Clindamycin; Tretinoin? (Back to top) •erythromycin-containing products •other acne products including benzoyl peroxide or salicylic acid •skin cleansers or medicated soaps •medicated cosmetics, including cover-up preparations •skin care products that have a high alcohol content (some shaving creams, lotions, or after shave lotion) •other skin products that contain alcohol, astringents, spices or lime Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines. What side effects may I notice from receiving Clindamycin; Tretinoin? (Back to top) Side effects that you should report to your prescriber or health care professional as soon as possible: •crusting or swelling of the treated areas •diarrhea that is watery or severe •excessive or persistent burning, stinging or itching of the treated areas •pain on swallowing •stomach pain or cramps •unusual or persistent rash or skin reaction Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome): •dry skin •red, inflamed, and irritated skin, the skin may peel after a few days •increased sensitivity to the sun •darkening or lightening of the treated areas What should I watch for while taking Clindamycin; Tretinoin? (Back to top) Acne should get better in about 6 weeks. Complete improvement may take longer. Tell your doctor or health care professional if you do not improve. Your skin may get very dry and scale or peel. Let your doctor or health care professional know if this happens. Do not use any soothing cream or ointment without advice. Do not wash your face more than 2 or 3 times a day. Do not use the following products on the same areas that you are treating with this medicine, unless otherwise directed by your doctor or health care professional: other topical agents with a strong skin drying effect like products with a high alcohol content, astringents, spices, the peel of lime or other citrus, medicated soaps or shampoos, permanent wave solutions, electrolysis, hair removers or waxes, or any other preparations or processes that might dry or irritate your skin. Ask your doctor or healthcare professional before using these products. This medicine can make you more sensitive to the sue. If you cannot avoid being in the sun, wear protective clothing and use a sunscreen (SPF 15 or higher). Do not use sun lamps or tanning beds/booths. Where can I keep my medicine? (Back to top) Keep out of the reach of children. Store at room temperature, between 15 and 30 degrees C (59 and 86 degrees F). Do not freeze. Keep away from heat and protect from light. Keep the tube tightly closed. Last Updated:11/22/2006 CLINICAL PHARMACOLOGY© GOLD STANDARD MULTIMEDIA INC, ALL RIGHTS RESERVED

Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It should not be construed to indicate that the use of the product is safe, appropriate, or effective for you. Consult your healthcare professional before taking the product.